What are Polynucleotides: Everything you need to know

PDRN: polynucleotides in modern cosmetology

One of the trends in modern cosmetology is natural rejuvenation. Today, preparations that are biologically compatible with the tissues of our body are at the peak of popularity. These include cosmetic products based on Polynucleotides (PDRN). 

Polynucleotides are complex proteins that are the structural units of our DNA. In other words, it is the building material, the bricks that restore our damaged DNA cells. They are able to stimulate the synthesis of new skin cells and, as a result, restore their youth. The use of polynucleotides in cosmetology is a fundamentally new and unique technology as it fights not the signs but the causes of aging.

The natural process of aging is closely related to the fact that the body loses its ability to produce fibroblasts. These are the cells that synthesize collagen, elastin, hyaluronic acid and other components in healthy tissues. When there are few fibroblasts, Polynucleotides come to help!

Polynucleotides for your face

 

The use of Polynucleotides in cosmetology covers a wide range of dermatological problems and skin imperfections. A sufficient amount of elastin and collagen is important at any age and is especially valuable for aged skin. The anti-inflammatory action of Polynucleotides is indispensable for skin regeneration in the process of treating acne and scars of various origins.

Facial mesotherapy with polynucleotides triggers metabolism and regeneration in affected skin cells. Thanks to this, preparations with PDRN have a complex effect, namely:

– Increase skin elasticity, provide an excellent lifting effect. Preparations based on Polynucleotides activate the synthesis of collagen and elastin fibers. 

– Moisturize and hydrate your skin. Polynucleotides have unique hydrating qualities, they increase the synthesis of hyaluronic acid.

– Restore cells. They speed up the healing of damaged tissues and start the process of the formation of blood vessels.

– Have an antioxidant effect. Polynucleotides reduce the effect of free radicals.

– Have an anti-inflammatory effect. Thanks to this, they improve the therapy of problematic skin.

– Protect against ultraviolet radiation, fight existing pigment and stagnant spots. They also reduce melanin production in cells.

 

Moreover, polynucleotides are widely used on different parts of the body. They work perfectly on the neck, décolleté, hands and scalp (hair mesotherapy).

 

Polynucleotides for the area around your eyes

 

The skin around your eyes ages the fastest. This is because it is thin, less elastic and constantly exposed to active facial expressions. Therefore, age-related changes can show up even at a young age.

Despite these factors, beauty shots (injections) under your eyes allow for improving skin density – that is why they work as a prevention of age-related changes.

Mesotherapy around the eyes is recommended for the following problems:

• dark circles under the eyes;
• “crow’s feet” and wrinkles; 
• puffiness under the eyes; 
• droopiness of the upper eyelids; 
• age-related skin changes (reduced elasticity, dryness, etc.);
• unhealthy skin color of the periorbital zone;
• rehabilitation after surgical operations, aggressive types of peeling, laser skin resurfacing, blepharoplasty.

Thanks to mesotherapy, your skin becomes denser, a new framework of collagen fibers is created in it, which significantly rejuvenates and gives it a fresh, rested look. So, if you are looking for magic shots (injections) of beauty against bags under your eyes, wrinkles and a tired look, then biorevitalization with Polynucleotides is just for you.

 

What effect can be expected from the use of Polynucleotides?

Polynucleotide injections for the face are effective for getting the following results:

• increasing skin elasticity; 
• deep hydration;
• lifting effect;
• improving skin texture, pores tightening;
• reducing scars and acne marks;
• reducing vascular network;
• reducing inflammations. 

 

Biorevitalization around the eyes works for:

– reducing dark circles and puffiness under the eyes;

– reducing wrinkles, creases and so-called crow’s feet; 

– reducing droopiness of the upper lids;

– reducing skin dryness.

 

Scalp mesotherapy results in:

– reducing hair loss;

– stimulation of follicles for new hair growth.

 

As for the neck and décolleté:

– reducing flabbiness of the skin; 

– removing small wrinkles and creases;

– reducing or removing so-called “Venus rings”;

– lifting, shaping facial contours.  

 

Preparations based on Polynucleotides are completely safe, however, like all cosmetic products, they have a number of contraindications:

• Pregnancy or lactation,
• Diabetes,
• Rheumatism, 
• Skin damage in the area of injections, 
• Infectious diseases.

Individual intolerance of one of the components of the preparation is also an obstacle to the procedure.

 

Reviews of Polynucleotide injections

Over the course of mesotherapy for the face, we have collected a lot of positive feedback from our clients. You can’t help but admire the visible and natural result of rejuvenation without the effect of injection interventions. The main sign of satisfaction of our clients is their desire to repeat the course of procedures with the preparations based on Polynucleotides. The first thing that our clients notice is the tightening of pores and improving skin density as if it has become thicker and more elastic. Over time, they notice a reduction of wrinkles and creases, hydration and excellent seboregulation, lifting and evening out of skin tone. In cases of work with acne and acne marks – their reduction or complete removal.

 

The effectiveness of injections directly depends on the number and frequency of procedures. Depending on the problem with which the patient comes to our clinic, various options for fighting against skin defects may be offered. Biorevitalization with Polynucleotides can be used alone or in combination with other procedures – facial contouring, peelings, laser procedures and others. A combination of procedures will increase their effectiveness and reduce the rehabilitation period and possible complications. The procedure is all-season, ideal for restoring your skin in summer when many laser and acid procedures are not recommended.

The recommended course of biorevitalization with Polynucleotides is 3-5 procedures with an interval of 3-4 weeks. It is advisable to repeat this course every six months to prolong the effect.

 

Rejuran polynucleotides

The Clinic of Aesthetic Medicine of Myroslava Novosilska uses preparations of premium quality from the proven manufacturers – Rejuran (South Korea), Twac (Great Britain), Mastelli (Italy). During the consultation, an experienced cosmetologist finds out the client’s needs, thoroughly examines the skin and prescribes a course of biorevitalization specifically for the client’s skin type, age and problems.

 

We give preference to the preparations of these manufacturers as they have proven to be the most effective. Each of the manufacturers pays great attention to the reliability of their products. Before the components got into a syringe, numerous in vitro and in vivo studies, as well as clinical trials had been conducted in the laboratories of Europe, Asia, and Ukraine in order to be properly certified. Therefore, these pharmaceutical-grade polynucleotides visibly improve skin condition after the first procedure.

 

The cost of Polynucleotide biorevitalization of the face varies from UAH 4,000 to UAH 8,000 per session. The same price will cover the neck and hands. The price of beauty shots (injections) under the eyes is UAH 4,000-4,600 per session. Biorevitalization of the scalp is UAH 6,410.

What is the difference between biorevitalization with Polynucleotides and biorevitalization with Hyaluronic acid?

 

Polynucleotide biorevitalization and classical biorevitalization with hyaluronic acid are similar procedures. However, they have a fundamentally different mechanism of action on skin cells. 

 

Birevitalization with Hyaluronic acid gives an instant hydrating effect. The result of the procedure is seen immediately. It can be used on all parts of the face and some parts of the body. It must be used cautiously around the eyes.

The preparation activates the work of fibroblasts stimulating the production of collagen and elastin.

 

Biorevitalization procedures with Polynucleotides stimulate the work of fibroblasts much more powerfully, which also activates the production of collagen and elastin. Moreover, it stimulates metabolic processes in cells, activating the production of hyaluronic acid and skin self-regeneration. Such biorevitalization is perfect as a prevention of early aging, for the neck and décolleté areas, biorevitalization of the scalp and hands. Shots (injections) under the eyes with Polynucleotides work best.

 

It has a more complex mechanism of action and requires several days for a visible result to show up. But the effect is more long-lasting and stable. Thus, polynucleotides solve the problem at the level of the causes of aging, which cannot be said about the classical biorevitalization with Hyaluronic acid.

 

No wonder that Biorevitalization with Polynucleotides is currently at the peak of popularity. The cutting-edge technologies make it possible to restore the proper functioning of the skin and return the lost appearance without traces of injection and plastic intrusion. Preparations based on Polynucleotides have been developed exactly for such purposes.